Parathyroid hormone gene-activated matrix with DFDBA/collagen composite matrix enhances bone regeneration in rat calvarial bone defects
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چکیده
منابع مشابه
The Efficacy of Implant of Octacalcium Phos-phate in Combination with Bone Matrix Gelatin on Bone Regeneration in Skull Defects in Rat
Background: In several conditions we have face cranial bone defects. Reconstruction of these defects remains one of the most challenging problems encountered by craniofacial surgeons. Objective: To evaluate bone repair in cranial bone defects by use of an implant made of octacalcium phosphate in combination with bone matrix gelatin (OCP/BMG). Methods: We used 40, 5–6-week-old male Sprague-Dawle...
متن کاملGrowth hormone treatment promotes guided bone regeneration in rat calvarial defects.
This study evaluated the biomechanical strength and bone formation in calvarial critical size bone defects covered with expanded polytetrafluoroethylene (e-PTFE) membranes in rats treated systemically with recombinant human growth hormone (rhGH). A full-thickness bone defect, 5 mm in diameter, was trephined in the central part of each parietal bone in 40 one-year-old female Wistar rats, which w...
متن کاملHistomorphometric Analysis of Newly-formed Bone Using Octacalcium Phosphate and Bone Matrix Gelatin in Rat Tibial Defects
Background: Repair of bone defects is challenging for reconstructive and orthopedic surgeons. In this study, we aimedto histomorphometrically assess new bone formation in tibial bone defects filled with octacalcium phosphate (OCP),bone matrix gelatin (BMG), and a combination of both.Methods: A total of 96 male Sprague Dawley rats aged 6-8 weeks weighing 120-150 g were randomly allocatedinto thr...
متن کامل"repair of cranial bone defects using endochondral bone matrix gelatin in rat "
bone matrix gelatin (bmg) has been used for bone induction intramuscularly and subcutaneously by many investigators since 1965. more recently, some of the researchers have used bmg particles for bone repair and reported various results. in present study for evaluation of bone induction and new bone formation in parital defects, bmg particles were used in five groups of rats. the bmg was prepare...
متن کاملDemineralized dentin matrix combined with recombinant human bone morphogenetic protein-2 in rabbit calvarial defects
OBJECTIVES The aim of this study was to compare the osteogenic effects of demineralized dentin matrix (DDM) combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) in rabbit calvarial defects with DDM and anorganic bovine bone (ABB) combined with rhBMP-2. MATERIALS AND METHODS Four round defects with 8-mm diameters were created in each rabbit calvaria. Each defect was treated w...
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ژورنال
عنوان ژورنال: Journal of the Chinese Medical Association
سال: 2018
ISSN: 1726-4901
DOI: 10.1016/j.jcma.2017.12.004